Custom Peptides
Cayman Chemical MonbromobImn 10mg
A thiol-reactive fluorogenic probe; used to evaluate or quantify a variety of compounds containing reactive sulfur or thiol groups, including H2S, glutathione, proteins, and nucleotides
Cayman Chemical 6-deoxy-L-Talose 10mg
A microbial monosaccharide; has been found in the cell wall of bacteria such as S. bovis and in the O-specific polysaccharide of LPS in species including E. coli and P. maltophilia; a component of the surface glycopeptidolipids of M. avium
Cayman Chemical GnoderIc AcId B 10mg
A triterpenoid with diverse biological activities; inhibits HIV-1 protease (IC50 = 0.17 mM); cytotoxic to HepG2 and Caco-2 cells (IC50s = 0.65 and 0.36 mg/ml, respectively); inhibits acetic acid-induced writhing in mice by 48.3% at 5 mg/kg
Cayman Chemical Fenobamhydrate 10mg
A noncompetitive antagonist and inverse agonist of mGluR5 that binds to an allosteric site; inhibits quisqualate-induced intracellular calcium mobilization in HEK293 cells expressing the human receptor (IC50 = 58 nM); inhibits basal activity of mGluR5 in a cell-based assay (IC50 = 84 nM); reduces stress-induced hyperthermia in mice at 10 and 30 mg/kg; increases drinking time in the Vogel conflict test in rats at 30 mg/kg; induces analgesia in the formalin test in mice at 30 mg/kg
Cayman Chemical CInserInhydrochlorIde 10mg
A 5-HT receptor antagonist; inhibits 5-HT-induced effects on isolated rat uterus but not guinea pig ileum; inhibits 5-HT-induced gross excitation, gastric mucosal erosion, and anaphylactoid edema in mice and rats; impairs acquisition of a running response in rats trained for food reward at 12 and 36 mg/kg; inhibits SARS-CoV 3CLpro (IC50 = 5 µM); reduces SARS-CoV viral RNA levels in infected BHK-Rep-1 cells (IC50 = 19-34 µM)
Cayman Chemical Muricholic ACD 10mg
A murine-specific primary bile acid; dietary administration reduces HMG-CoA reductase activity in liver microsomes from mice fed a high cholesterol and cholic acid diet; dietary administration dissolves 100% of gallstones in a gallstone-susceptible mouse model of diet-induced cholesterol gallstones
Cayman Chemical 6-bromo-MDMAhydrochlorIde 10mg
Differs structurally from 3,4-MDMA in that it has a bromine group added at the two position of the phenyl ring
Cayman Chemical TrelaglIptIn 10mg
A DPP-4 inhibitor (IC50 = 4 nM)>10,000-fold selective for DPP-4 over isopeptidases; inhibits plasma DPP-4 activity and reduces postprandial plasma insulin levels in Zucker fa/fa rats at 7 mg/kg
Cayman Chemical -CloprostenolsodIum salt 10mg
(+)-Cloprostenol (sodium salt) is a more water soluble, crystalline form of (+)-cloprostenol.
Cayman Chemical MocetInostat 10mg
An orally available HDAC inhibitor that selectively targets HDAC1 and 2 (IC50s = 0.15 and 0.29 µM, respectively), less potently inhibits HDAC3 and 11 (IC50s = 1.66 and 0.59 µM, respectively); induces hyperacetylation of histones, causes cell cycle blockade, and induces apoptosis in cancer cells in vitro
Cayman Chemical Seco RapamycInsodIum salt 10mg
A nonenzyme-dependent degradation product of rapamycin resulting from ester hydration followed by dehydration; secreted from cells by P-glycoprotein; poorly activates mTOR but, like rapamycin, inhibits the proteasome
Cayman Chemical Taurolthocholc ACD 3sulfa 10mg
A metabolite of taurolithocholic acid; has been used to study bile acid transport in cellular models and to induce pancreatitis in mouse models of bile acid infusion pancreatitis
Cayman Chemical BeraprostsodIum salt 10mg
Beraprost is an analog of prostacyclin in which the unstable enol-ether has been replaced by a benzofuran ether function. This modification increases the plasma half-life from 30 seconds to several hours, and permits the compound to be taken orally. Doses of 20-100 UG in humans, given 1 to 3 times per day, have been demonstrated to improve clinical end points in diseases responsive to prostacyclin. Oral beraprost therapy improved the survival and pulmonary hemodynamics of patients with primary pulmonary hypertension.{8136} Beraprost inhibits platelet aggregation in healthy subjects and in diabetic patients at similar doses.{8137,8139}
Cayman Chemical 4mthylN NDImthylcathInon 10mg
An analytical reference standard categorized as a cathinone; intended for research and forensic applications
Cayman Chemical 5-trns Latnoprost 10mg
A derivative of latanoprost (free acid), an isomer of latanoprost, and an analytical standard; may have similar biological activities as F-type prostaglandin cis isomers; a potential impurity in commercial preparations of latanoprost; intended as an analytical standard